A new AI-powered framework for rendering natural, realistic focus effects in VR. DeepFocus works with advanced prototype headsets, rendering blur in real time and at various focal distances. For example, when someone wearing a DeepFocus-enabled headset looks at a nearby object, it immediately appears crisp and in focus, while background objects appear out of focus, just as they would in real life. This defocused blur (also known as retinal blur) is important for achieving realism and depth perception in VR. DeepFocus is the first system able to produce this effect in real time for VR applications. We are now open-sourcing our work and data set to help others in the VR research community.